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FDA approves first drug to target a genetic root of pancreatic cancer

8/26/2026

The Food and Drug Administration approved a life-extending treatment for advanced pancreatic cancer on Wednesday, the first drug designed to block a genetic driver of the disease.

A genetic driver, in plain terms, is a mutation that acts like a standing order inside cancer cells, telling them to multiply without stopping.

Revolution Medicines, a biotech company, will market the treatment under the brand name Rasonque; the drug's scientific name is daraxonrasib.

Rasonque's approval rested on a clinical trial that produced results earlier this year. The trial enrolled patients who had already gone through one round of therapy that did not work, a setting called second-line.

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